Pregnancy by Assisted Reproductive Technology Is Associated with Shorter Telomere Length in Neonates

Telomere length (TL) influences the development of lifestyle-related diseases, and neonatal TL may influence their prevalence. Various factors have been reported to affect neonatal TL. Although the fetus is exposed to multiple conditions in utero, the main factors affecting the shortening of neonatal TL are still not known. In this study, we sought to identify factors that influence fetal TL. A total of 578 mother-newborn pairs were included for TL analysis. TL was measured in genomic DNA extracted from cord blood samples using quantitative PCR. The clinical factors examined at enrollment included the following intrauterine environmental factors: maternal age, assisted reproductive technology (ART) used, body mass index (BMI), gestational diabetes mellitus (GDM), maternal stress, smoking, alcohol consumption, preterm delivery, small-for-gestational-age, neonatal sex, and placental weight. Univariate and multivariate regression analyses were used to verify the relationship between neonatal TL and these clinical factors. The median neonatal TL to single-copy gene ratio was 1.0. Pregnancy with ART was among the 11 factors associated with shorter neonatal TL. From multiple regression analysis, we determined that neonatal TL was significantly shorter for pregnancies in the ART group than in the other groups. We conclude that pregnancy with ART is associated with shorter neonatal TL.     

机械结构分层优化技术研究进展

复杂机械结构优化设计一般表现为多目标、多约束、多参数的优化问题,所以复杂结构优化设计过程通常存在计算复杂、不易收敛等困难。分层优化技术是复杂结构优化设计的一种有效途径,通过将优化问题中复杂的约束、设计变量以及功能目标合理分解为若干子层问题进行求解,然后通过协调得到复杂机械结构整体优化问题的结果。文章对机械结构分层优化技术的理论、应用研究现状进行了总结并探讨了其关键技术环节及发展趋势。     

长管拖车缠绕气瓶纤维层冲击损伤的数字射线检测

采用缠绕气瓶替代钢制无缝气瓶是长管拖车轻量化的重要手段之一,但对于缠绕气瓶缠绕层因冲击造成的内部损伤,目前仍缺少成熟有效的检测手段。采用数字射线检测方法,针对玻璃纤维缠绕层冲击损伤造成的分层和危害较大的纤维断裂进行了试验研究。试验表明,采用数字射线检测能够有效检测最小深度为0.5 mm模拟纤维环向断裂刻槽和0.25 mm的模拟纤维轴向断裂刻槽;此外,还通过试验验证增加补偿块的方式,能极大地改善缠绕层分层部位的一次切向透照成像质量,进而提高检测效率。     

雨林地区米拉多铜矿排土场碾压堆石坝施工技术

随着社会经济的发展，如何合理、有序、经济、环保地处理弃土弃渣已成为强降雨地区土石方项目亟需解决的问题。而对于雨林地区土石方工程往往需要布设大面积的排土场进行弃土弃渣，弃土弃渣存在“量大、集中”等特点。为保证弃土有效容量，排土场往往设置在沟谷中，雨林地区排土场如何保证地基处理、渗流层施工、分层填筑碾压是坝体施工质量控制的关键所在。以厄瓜多尔米拉多铜矿采矿工业场地工程项目为例，该项目存在土石方开挖工程量大，项目面临雨季长、高雨频等突出气候特点。项目排土场设计为碾压堆石坝，坝体整体高度84.8 m，坝体填筑石方达27.8万m3。简要介绍了该工程1 095 m排土场坝体施工的特点和难点，叙述坝体施工过程中采取的主要关键技术，为类似的工程施工提供借鉴。     

三维激光扫描技术在矿山主溜井测量中的应用

溜井测量具有一定的隐蔽性和不确定性,测量时有相当的危险性,如何对溜井的空间形态特征和冒落状况等进行量化评判,是所有矿山面临的难题。本文介绍了三维激光扫描技术的作业流程,给出了点云数据处理的过程和方法,并以安徽开发矿业有限公司3#主溜井测量为例进行数据采集和处理分析,建立了主溜井的三维立体模型,计算得到了主溜井需要修复的体积,为溜井的安全治理和维修设计提供了可靠的数据依据。实践结果表明了三维激光扫描技术在溜井测量中应用的可行性和优越性。     

Ethics,society, and technology: A Confucian role ethics perspective

This essay provides a very brief overview of Confucian ethics that focuses on the role-based morality. It compares Confucian ethics with two dominant schools of thought in Western ethics deontology and consequentialism. This essay then discusses how Confucian ethics provides a unique way to think about social and political issues such as how the political leaders are selected and evaluated, the ethical justification of political legitimacy, the prioritization of economic, social, and cultural rights over other rights, and moral egalitarianism. Finally, this essay explores the ways in which Confucian ethics serves as a useful intellectual resource for examining the issues arising from the ethical assessment of (emerging) technologies and the professional formation of engineers. The Appendix of this essay includes some teaching resources that instructors can employ to teach students about ethics, society, and technology from a Confucian role ethics perspective.     

云计算在智慧医院信息服务中的应用

随着医疗服务体系的发展和进步,越来越多的医院开始将云计算技术引入信息服务系统,使医院信息化建设得到了迅速发展。文章分析了云计算技术的特点及其在智能医院信息服务中的应用和影响,以期促进该技术在未来的发展和推广。     

信息技术在医院病案统计中的应用

伴随着我国综合实力的不断提升,信息技术获得了突飞猛进的发展,如今,医疗改革如火如荼地进行,医院的信息管理工作同以往相比较也实现了极大的发展。病案统计工作是指相关工作人员对医院中患者的信息进行全面统计,若是这项工作完成得足够出色,会给医院后续的信息查询工作带来诸多方便和快捷,也能够在某种程度上使医院管理效率和质量实现一定幅度的提升。因此,将信息技术和医院的病案工管理工作进行密切结合,就成为病案管理人员应当重点思考的问题。病案统计工作是医院管理工作中的一个重点环节,病案统计结果能够为医院整体绩效带来十分深远的影响。因此,投入更多时间和精力来提高对这项工作的重视,显得十分关键和重要。文章对信息技术在医院病案统计中的应用展开了分析。     

耦合让均压支护在综采面端头维护的应用

为了提高综采工作面端头超前应力区顶板稳定性,降低顶板支护费用,对8309工作面端头应力区提出了耦合让均压支护技术,控制了端头应力区顶板下沉、破碎现象,可降低支护成本费用320元/m。     

某油田油井采出水腐蚀因素研究

我国油田油井生产中采油井管柱腐蚀现象十分普遍,所以在注CO_2驱进行开采过程中要进行采出水的质量分析。对现阶段的油田生产腐蚀及防腐技术进行论述,提出相对应的防腐措施,进一步为油田生产作业提高产量。